| ORF ID | TF00803 (frame 1) |
Gene ID | lpg2687 |
| Position and sequences | 3037576...3038031(151 aa) |
Gene Name/synonym |
icmV
- |
| Organism | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 |
Cluster |
4 genes |
| Product | Type IV secretion system protein IcmV |
| 1stcategory | I-T4SS |
2ndcategory | Uncharacterized Protein Family IcmV |
| 3rdcategory | Effector translocator |
| Function | Component of the type IV secretion system Dot/Icm that is required for intracellular growth in human macrophages and amoebae. |
| Miscellaneus | Probably is a membrane-associated protein;
Present in a region of 7 genes (called Region I) that is required for human macrophage killing and intracellular multiplication in L. pneumophila;
Organized on a transcriptional unit icmV-dotA;
|
| References |
PubMed:12081952
PubMed:17040490
PubMed:15271914
PubMed:15003709
PubMed:14715899
PubMed:10225863
PubMed:9488381
PubMed:9465074
|