ORF ID | TF00799 (frame 1) |
Gene ID | lpg2674 |
Position and sequences | 3021320...3021811(163 aa) |
Gene Name/synonym |
dotD
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Organism | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 |
Cluster |
4 genes |
Product | Type IV secretion system protein DotD |
1stcategory | I-T4SS |
2ndcategory | Uncharacterized Protein Family DotD |
3rdcategory | Effector translocator |
Function | Component of the type IV secretion system Dot/Icm that is required for intracellular growth in human macrophages and amoebae. Together with DotC is required for outer membrane association of DotG and DotF. |
Miscellaneus | Similarity with TraH from L. pneumophila;
DotD lipoprotein is localized at the outer membrane;
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References |
PubMed:16239561 
PubMed:17040490 
PubMed:15271914 
PubMed:15003709 
PubMed:14715899 
PubMed:12081952 
PubMed:10225863 
PubMed:9488381 
PubMed:9465074 
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