ORF information
ORF ID TF00079 (frame 1) Gene ID HP0525
Position and sequences 552472...553464(330 aa) Gene Name/synonym virB11 /cag-apha
Organism Helicobacter pylori 26695 Cluster 206 genes
Product Type IV secretion system protein VirB11 homolog
1stcategory P-T4SS 2ndcategory VirB11/TrbB/GspE Family
3rdcategory Effector translocator
Function Component of the type IV secretion system Cag/Vir, which is enconded in the cag patogenicity island PAI. The type IV secretion system Cag/Vir translocates the immunodominant antigen CagA protein into the cytosol of gastric epithelial cells. VirB11 probably binds ATP.
Miscellaneus
References PubMed:11796597 

Functional Annotation
  KEGG database
Organism H.pylori_HPAG1 Gene entry HPAG1_0500
Gene name Synonyms
Definition cag pathogenicity island encoded protein/ATPase protein
Class hpa05120]
Classification Unassigned
DBLinks GeneID 4097934 GI 108562925 UniProt Q1CU05
 
  COG Clusters of Orthologous Groups of proteins
 
Gene Classification Coords (size) Product
N 24 .. 330 (307) Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis

Blast results (KEGG)
H.pylori_HPAG1 :  BlastP (output)
Score Expect Query coverage Subject coverage
666 0.0 100 100
57 7e-07 78.7172 83.7423

InterPro
Evidence ID Name Loci start-end InterPro ID InterPro Name
HMMTigr TIGR02788 VirB11: P-type DNA transfer ATPase VirB11 [ 0 - 326 ] IPR014155 P-type DNA transfer ATPase VirB11
BlastProDom PD000739 Q9ZLV2_HELPJ_Q9ZLV2; [ 0 - 242 ] IPR001482 Type II secretion system protein E
HMMPfam PF00437 GSPII_E [ 0 - 320 ] IPR001482 Type II secretion system protein E

GO (Gene Onthology)
ID Type Description
0005524 Molecular Function ATP binding
0005622 Cellular Component intracellular
0006810 Biological Process transport
0005524 Molecular Function ATP binding
0005622 Cellular Component intracellular
0006810 Biological Process transport

Blast Results (Swiss-Prot)
Score Expect Coverage Query Coverage Subject Accesion Number Product (Click to view blast result)
165 2e-40 91.5152 91.9668 Q8FXK7 Type IV secretion system protein virB11

Topology
 
PHOBIUS txt

Protein localization analysis
 
Psort bacterial inner membrane-0.2741-Affirmative (output)