ORF information
ORF ID TF00789 (frame 1) Gene ID lpp2729
Position and sequences 3108872...3109783(303 aa) Gene Name/synonym dotC -
Organism Legionella pneumophila Paris Cluster 6 genes
Product Type IV secretion system protein DotC
1stcategory I-T4SS 2ndcategory Uncharacterized Protein Family DotC
3rdcategory Effector translocator
Function Component of the type IV secretion system Dot/Icm that is required for intracellular growth in human macrophages and amoebae. Together with DotD is required for outer membrane association of DotG and DotF.
Miscellaneus Similarity with TraI from L. pneumophila. DotC contain a lipobox motif at their N-terminal and is predicted to be a lipoprotein.
References PubMed:16239561  PubMed:17040490  PubMed:15271914  PubMed:15003709  PubMed:14715899  PubMed:12081952  PubMed:10225863  PubMed:9488381  PubMed:9465074 

Functional Annotation
  KEGG database
Organism L.pneumophila_Paris Gene entry lpp2729
Gene name dotC Synonyms
Definition defect in organelle trafficking lipoprotein DotC
Classification Unassigned
DBLinks GeneID 3119527 GI 54298665 Pasteur lpp2729 UniProt Q5X1L4
 
 
COG No results found !

Blast results (KEGG)
L.pneumophila_Paris :  BlastP (output)
Score Expect Query coverage Subject coverage
602 e-171 100 100

InterPro
Evidence ID Name Loci start-end InterPro ID InterPro Name
ProfileScan PS51257 PROKAR_LIPOPROTEIN [ 0 - 19 ] NULL NULL
GO (Gene Onthology)
 
GO No results found !
Blast Results (Swiss-Prot)
 
Blast Results (Swiss-Prot) No results found !

Topology
 
PHOBIUS txt

Protein localization analysis
 
Psort bacterial outer membrane-0.79-Affirmative bacterial inner membrane-0.7663-Affirmative (output)