| ORF ID | TF00788 (frame 1) |
Gene ID | lpl2602 |
| Position and sequences | 2968608...2969519(303 aa) |
Gene Name/synonym |
dotC
- |
| Organism | Legionella pneumophila Lens |
Cluster |
6 genes |
| Product | Type IV secretion system protein DotC |
| 1stcategory | I-T4SS |
2ndcategory | Uncharacterized Protein Family DotC |
| 3rdcategory | Effector translocator |
| Function | Component of the type IV secretion system Dot/Icm that is required for intracellular growth in human macrophages and amoebae. Together with DotD is required for outer membrane association of DotG and DotF. |
| Miscellaneus | Similarity with TraI from L. pneumophila;
DotC contain a lipobox motif at their N-terminal and is predicted to be a lipoprotein.
|
| References |
PubMed:16239561
PubMed:17040490
PubMed:15271914
PubMed:15003709
PubMed:14715899
PubMed:12081952
PubMed:10225863
PubMed:9488381
PubMed:9465074
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