ORF ID | TF00787 (frame 1) |
Gene ID | lpg2675 |
Position and sequences | 3021792...3022703(303 aa) |
Gene Name/synonym |
dotC
- |
Organism | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 |
Cluster |
6 genes |
Product | Type IV secretion system protein DotC |
1stcategory | I-T4SS |
2ndcategory | Uncharacterized Protein Family DotC |
3rdcategory | Effector translocator |
Function | Component of the type IV secretion system Dot/Icm that is required for intracellular growth in human macrophages and amoebae. Together with DotD is required for outer membrane association of DotG and DotF. |
Miscellaneus | Similarity with TraI from L. pneumophila;
DotC contain a lipobox motif at their N-terminal and is predicted to be a lipoprotein.
|
References |
PubMed:16239561 
PubMed:17040490 
PubMed:15271914 
PubMed:15003709 
PubMed:14715899 
PubMed:12081952 
PubMed:10225863 
PubMed:9488381 
PubMed:9465074 
|