| ORF ID | TF00783 (frame 1) | Gene ID | BAA97959 |
| Position and sequences | 1...602(602 aa) | Gene Name/synonym | traN - |
| Organism | Plasmid F | Cluster | 4 genes |
| Product | F-type conjugal transfer protein TraN | ||
| 1stcategory | F-T4SS | 2ndcategory | TraN-F Family |
| 3rdcategory | Conjugation | ||
| Function | Component of the conjugative T4SS trb/tra required for the transfer of plasmid F among E. coli cells, from donor cells to recipients. The TraN is an outer-membrane protein involved in mating pair stabilization (MPS). | ||
| Miscellaneus | TraN appears to have two domains: the N-terminal region is involved in OmpA interaction with OmpA during MPS; and the C-terminal region, which is rich in conserved cysteine residues, is essential for conjugation. The C-terminal region is also important for TraN function, with disulfide bond formation probably playing an important role. Contact with OmpA could mediate the formation of the conjugative pore whereby a complex containing TraG, and perhaps other transfer proteins, forms the channel between the cytoplasm of the donor and recipient cells. | ||
| References | PubMed:16272376 | ||
| KEGG Database | No results found ! | ||
| COG | No results found ! | ||
|
| GO | No results found ! | ||
|
| PHOBIUS | txt | ||
| Psort | (output) | ||