ORF information
ORF ID TF00060 (frame 1) Gene ID BRA0059
Position and sequences 56802...57887(361 aa) Gene Name/synonym virB11 /virB11s
Organism Brucella suis 1330 Cluster 206 genes
Product Type IV secretion system protein VirB11 homolog
1stcategory P-T4SS 2ndcategory VirB11/TrbB/GspE Family
3rdcategory Effector translocator
Function The VirB T4SS could be required for the establishment of the replication niche in the host. VirB11 may be multimeric inner-membrane-localized NTPase, which could traverse the inner membrane to contact periplasmic VirB proteins.
Miscellaneus VirB system is specifically induced within macrophages by phagosome acidification. Induced at 37 degrees Celsius in minimal medium, suggesting that nutritional stress is a regulating signal. VirB11 interacts with VirB1.
References PubMed:11830669  PubMed:16272371 

Functional Annotation
  KEGG database
Organism B.suis Gene entry BRA0059
Gene name virB Synonyms 11
Definition type IV secretion system protein VirB11
Class Genetic Information Processing; Sorting and Degradation; Type IV secretion system [PATH:bms03080]
Classification Sorting and Degradation
DBLinks GeneID 1164496 GI 23499826 TIGR BRA0059 UniProt Q8FXK7
 
  COG Clusters of Orthologous Groups of proteins
 
Gene Classification Coords (size) Product
N 17 .. 360 (344) Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis

Blast results (KEGG)
B.suis :  BlastP (output)
Score Expect Query coverage Subject coverage
727 0.0 100 100

InterPro
Evidence ID Name Loci start-end InterPro ID InterPro Name
ScanRegExp PS00675 SIGMA54_INTERACT_1 [ 0 - 191 ] IPR002078 RNA polymerase sigma factor 54, interaction
HMMPfam PF00437 GSPII_E [ 0 - 332 ] IPR001482 Type II secretion system protein E
BlastProDom PD000739 Q9KIS5_BRUAB_Q9KIS5; [ 0 - 253 ] IPR001482 Type II secretion system protein E
HMMTigr TIGR02788 VirB11: P-type DNA transfer ATPase VirB11 [ 0 - 345 ] IPR014155 P-type DNA transfer ATPase VirB11

GO (Gene Onthology)
ID Type Description
0005524 Molecular Function ATP binding
0005622 Cellular Component intracellular
PS00675 361 ScanRegExp
PS00675 361 ScanRegExp
0008134 Molecular Function transcription factor binding
0005524 Molecular Function ATP binding
0005622 Cellular Component intracellular
0006810 Biological Process transport
0005524 Molecular Function ATP binding
0005622 Cellular Component intracellular
0006810 Biological Process transport

Blast Results (Swiss-Prot)
Score Expect Coverage Query Coverage Subject Accesion Number Product (Click to view blast result)
727 0.0 100 100 Q8FXK7 Type IV secretion system protein virB11

Topology
 
PHOBIUS txt

Protein localization analysis
 
Psort bacterial inner membrane-0.2359-Affirmative (output)