ORF ID | TF00513 (frame 1) | Gene ID | lpl0491 |
Position and sequences | 532729...533367(212 aa) | Gene Name/synonym | icmL /dotI |
Organism | Legionella pneumophila Lens | Cluster | 6 genes |
Product | Type IV secretion system protein IcmL/DotI | ||
1stcategory | I-T4SS | 2ndcategory | IcmL/DotI Family |
3rdcategory | Effector translocator | ||
Function | Component of the type IV secretion system Dot/Icm that is required for intracellular growth in human macrophages and amoebae. | ||
Miscellaneus | Localized in inner membrane. IcmL/DotI protein is similarity with TraM protein from IncI1 plasmid R64. TraM was described as a small DNA binding protein for the F-factor system. The R64 traMNU genes were absolutely required for R64 conjugation, while their homologues, icmLKB genes, were dispensable for RSF1010 mobilization in L. pneumophila. DotI is similar to the product, of unknown function, of orf3, located on the IncM plasmid R446; Insertion mutations in icmL gene had no effect on conjugation. | ||
References | PubMed:17040490  PubMed:15271914  PubMed:15003709  PubMed:14715899  PubMed:12081952  PubMed:10225863  PubMed:9488381  PubMed:9465074  PubMed:10760136  PubMed:15466052  |
KEGG database | |||
Organism | L.pneumophila_Corby | Gene entry | LPC_2894 |
Gene name | icmL | Synonyms | |
Definition | IcmL (DotI) | ||
Classification | Unassigned | ||
DBLinks | GeneID 5182672 GI 148360934 | ||
COG | No results found ! |
L.pneumophila_Corby : BlastP (output) | ||||||||
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InterPro | No results found ! |
GO | No results found ! |
Blast Results (Swiss-Prot) | No results found ! |
PHOBIUS | txt |
Psort | bacterial inner membrane-0.6074-Affirmative (output) |