ORF ID | TF00322 (frame 1) |
Gene ID | BRA0069 |
Position and sequences | 66525...67241(238 aa) |
Gene Name/synonym |
virB1
/virB1sp |
Organism | Brucella suis 1330 |
Cluster |
20 genes |
Product | Type IV secretion system protein VirB1 homolog |
1stcategory | P-T4SS |
2ndcategory | VirB1 Family |
3rdcategory | Effector translocator |
Function | The VirB T4SS could be required for the establishment of the replication niche in the host. VirB1 could act as a lytic transglycosylase, which facilitates the assembly of T4SS via localized lysis of the peptidoglycan. |
Miscellaneus | VirB system is specifically induced within macrophages by phagosome acidification. Induced at 37 degrees Celsius in minimal medium, suggesting that nutritional stress is a regulating signal.
VirB1 interacts with VirB8, VirB9 and VirB11.
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References |
PubMed:11830669 
PubMed:16272371 
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