| ORF ID | TF00315 (frame 1) |
Gene ID | AGR_pTi_3 |
| Position and sequences | 3047...3784(245 aa) |
Gene Name/synonym |
virB1
- |
| Organism | Agrobacterium tumefaciens C58 Cereon |
Cluster |
20 genes |
| Product | Type IV secretion system protein VirB1 |
| 1stcategory | P-T4SS |
2ndcategory | VirB1 Family |
| 3rdcategory | Effector and T-DNA translocator |
| Function | Component of the T4SS VirB/D4 required for the translocation of the virulence factors (VirE2, VirF and the VirD2-T-DNA complex) to plant cells. VirB1 is a bifunctional protein required for virT4SS assemby. The N-terminal lytic transglycosylase domain provides localized lysis of the peptidoglycan cell wall to allow insertion of the T4SS. The C-terminal VirB1* promotes T-pilus assembly through protein-protein interactions with T-pilus subunits. |
| Miscellaneus | The C-terminal third of the protein, VirB1* is cleaved from VirB1 and secreted by an unknwon mechanism.
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| References |
PubMed:17631630 
PubMed:10852875 
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