ORF information
ORF ID TF00296 (frame 1) Gene ID lpg1254
Position and sequences 1382136...1384616(826 aa) Gene Name/synonym lvhB4 -
Organism Legionella pneumophila subsp. pneumophila str. Philadelphia 1 Cluster 68 genes
Product Type IV secretion system protein VirB4 homolog
1stcategory P-T4SS 2ndcategory VirB4/TrbE/CagE Family
3rdcategory Conjugation and Effector translocator
Function Component of the type IV secretion system Legionella vir homologues (Lvh) that is partially required for conjugation. Also, the type IV system Lvh can act as an effector translocator preferentially involved in virulence-related phenotype under conditions mimicking the spread of Legionnaires's disease from environmental niches.
References PubMed:10564519  PubMed:17101653 

Functional Annotation
  KEGG database
Organism L.pneumophila Gene entry lpg1254
Gene name virB Synonyms 4
Definition LvhB4
Class Genetic Information Processing; Sorting and Degradation; Type IV secretion system [PATH:lpn03080]
Classification Sorting and Degradation
DBLinks GeneID 3077721 GI 52841486 UniProt Q5ZW33
  COG Clusters of Orthologous Groups of proteins
Gene Classification Coords (size) Product
U 12 .. 825 (814) Type IV secretory pathway, VirB4 components

Blast results (KEGG)
L.pneumophila :  BlastP (output)
Score Expect Query coverage Subject coverage
1665 0.0 100.0000 100.0000

Evidence ID Name Loci start-end InterPro ID InterPro Name
HMMTigr TIGR00929 VirB4_CagE: type IV secretion/conjugal tra [ 0 - 824 ] IPR004346 CagE, TrbE, VirB component of type IV transporter system
HMMPfam PF03135 CagE_TrbE_VirB [ 0 - 406 ] IPR004346 CagE, TrbE, VirB component of type IV transporter system

GO (Gene Onthology)
ID Type Description
0005524 Molecular Function ATP binding
0005524 Molecular Function ATP binding

Blast Results (Swiss-Prot)
Score Expect Coverage Query Coverage Subject Accesion Number Product (Click to view blast result)
352.0000 3e-96 98.3051 104.5918 Q9R2W4 Type IV secretion system protein virB4


Protein localization analysis
Psort (output)