ORF ID	TF00295 (frame 1)	Gene ID	HP0544
Position and sequences	575155...578106(983 aa)	Gene Name/synonym	cagE /virB4
Organism	Helicobacter pylori 26695	Cluster	68 genes
Product	Type IV secretion system protein VirB4 homolog
1stcategory	P-T4SS	2ndcategory	VirB4/TrbE/CagE Family
3rdcategory	Effector translocator
Function	Component of the type IV secretion system Cag/Vir, which is enconded in the cag patogenicity island PAI. The type IV secretion system Cag/Vir translocates the immunodominant antigen CagA protein into the cytosol of gastric epithelial cells. CagE is the inner membrane-localized ATPase that may provide the energy for substrate translocation.
Miscellaneus
References	PubMed:11796597

	KEGG database
Organism	H.pylori	Gene entry	HP0544
Gene name	cag2	Synonyms	3
Definition	cag pathogenicity island protein 23 (picb protein)
Class	Genetic Information Processing; Sorting and Degradation; Type IV secretion system [PATH:hpy03080]
Classification	Sorting and Degradation
DBLinks	GeneID 900243 GI 15645170 TIGR HP0544 UniProt Q48252
	COG Clusters of Orthologous Groups of proteins
	Gene Classification Coords (size) Product U 167 .. 983 (817) Type IV secretory pathway, VirB4 components

H.pylori :  BlastP (output)

Score Expect Query coverage Subject coverage 1955 0.0 100 100

Evidence ID Name Loci start-end InterPro ID InterPro Name HMMTigr TIGR00929 VirB4_CagE [ 0 - 980 ] IPR004346 CagE, TrbE, VirB component of type IV transporter system

ID Type Description 0005524 Molecular Function ATP binding

Score Expect Coverage Query Coverage Subject Accesion Number Product (Click to view blast result) 1955 0.0 100 100 Q48252 CAG pathogenicity island protein 23 (Protein picB)

PHOBIUS	txt

Psort	(output)