ORF information
ORF ID TF00290 (frame 1) Gene ID BRA0066
Position and sequences 62913...65408(831 aa) Gene Name/synonym virB4 /virB4s
Organism Brucella suis 1330 Cluster 68 genes
Product Type IV secretion system protein VirB4 homolog
1stcategory P-T4SS 2ndcategory VirB4/TrbE/CagE Family
3rdcategory Effector translocator
Function The VirB T4SS could be required for the establishment of the replication niche in the host. VirB4-VirB8 and VirB10-VirB8 interactions are required for B.suis biological activity.
Miscellaneus VirB system is specifically induced within macrophages by phagosome acidification. Induced at 37 degrees Celsius in minimal medium, suggesting that nutritional stress is a regulating signal.
References PubMed:11830669  PubMed:16648257 

Functional Annotation
  KEGG database
Organism B.suis Gene entry BRA0066
Gene name virB Synonyms 4
Definition type IV secretion system protein VirB4
Class Genetic Information Processing; Sorting and Degradation; Type IV secretion system [PATH:bms03080]
Classification Sorting and Degradation
DBLinks GeneID 1164503 GI 23499833 TIGR BRA0066 UniProt Q8FXK3
 
  COG Clusters of Orthologous Groups of proteins
 
Gene Classification Coords (size) Product
U 4 .. 831 (828) Type IV secretory pathway, VirB4 components

Blast results (KEGG)
B.suis :  BlastP (output)
Score Expect Query coverage Subject coverage
1691 0.0 100.0000 100.0000

InterPro
Evidence ID Name Loci start-end InterPro ID InterPro Name
BlastProDom PD013127 PD013127 [ 0 - 130 ] NULL NULL
HMMTigr TIGR00929 VirB4_CagE [ 0 - 819 ] IPR004346 CagE, TrbE, VirB component of type IV transporter system

GO (Gene Onthology)
ID Type Description
0005524 Molecular Function ATP binding

Blast Results (Swiss-Prot)
Score Expect Coverage Query Coverage Subject Accesion Number Product (Click to view blast result)
1691.0000 0.0 100.0000 100.0000 Q9RPY1 Type IV secretion system protein virB4

Topology
 
PHOBIUS txt

Protein localization analysis
 
Psort (output)