ORF ID | TF00278 (frame 1) |
Gene ID | Atu6170 |
Position and sequences | 185305...187674(789 aa) |
Gene Name/synonym |
virB4
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Organism | Agrobacterium tumefaciens C58 UWash |
Cluster |
68 genes |
Product | Type IV secretion system protein VirB4 |
1stcategory | P-T4SS |
2ndcategory | VirB4/TrbE/CagE Family |
3rdcategory | Effector and T-DNA translocator |
Function | Component of the T4SS VirB/D4 required for the translocation of the virulence factors (VirE2, VirF and the VirD2-T-DNA complex) to plant cells. VirB4 has both energetic and structural roles in substrate translocation. VirB4, VirB11 and VirD4 interact with each other, and that they promote substrate transfer by both ATP-independent and -dependent mechanisms. |
Miscellaneus | The hexameric VirB4 C-terminal domain resides in the periplasm and interacts with inner membrane Virb11 and periplasmic VirB8 and VirB10. N-terminal VirB4 interacts with cytoplasmic regions of VirD4 and VirB10.
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References |
PubMed:17038312 
PubMed:15554962 
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