ORF information
ORF ID TF00278 (frame 1) Gene ID Atu6170
Position and sequences 185305...187674(789 aa) Gene Name/synonym virB4 -
Organism Agrobacterium tumefaciens C58 UWash Cluster 68 genes
Product Type IV secretion system protein VirB4
1stcategory P-T4SS 2ndcategory VirB4/TrbE/CagE Family
3rdcategory Effector and T-DNA translocator
Function Component of the T4SS VirB/D4 required for the translocation of the virulence factors (VirE2, VirF and the VirD2-T-DNA complex) to plant cells. VirB4 has both energetic and structural roles in substrate translocation. VirB4, VirB11 and VirD4 interact with each other, and that they promote substrate transfer by both ATP-independent and -dependent mechanisms.
Miscellaneus The hexameric VirB4 C-terminal domain resides in the periplasm and interacts with inner membrane Virb11 and periplasmic VirB8 and VirB10. N-terminal VirB4 interacts with cytoplasmic regions of VirD4 and VirB10.
References PubMed:17038312  PubMed:15554962 

Functional Annotation
  KEGG database
Organism A.tumefaciens_C Gene entry AGR_pTi_8
Gene name virB Synonyms 4
Definition VIRB4 protein precursor
Class Genetic Information Processing; Sorting and Degradation; Type IV secretion system [PATH:atc03080]
Classification Sorting and Degradation
DBLinks GeneID 1142664 GI 16119786 UniProt P17794
  COG Clusters of Orthologous Groups of proteins
Gene Classification Coords (size) Product
U 9 .. 789 (781) Type IV secretory pathway, VirB4 components

Blast results (KEGG)
A.tumefaciens_C :  BlastP (output)
Score Expect Query coverage Subject coverage
1567 0.0 100.0000 100.0000

Evidence ID Name Loci start-end InterPro ID InterPro Name
HMMTigr TIGR00929 VirB4_CagE [ 0 - 784 ] IPR004346 CagE, TrbE, VirB component of type IV transporter system

GO (Gene Onthology)
ID Type Description
0005524 Molecular Function ATP binding

Blast Results (Swiss-Prot)
Score Expect Coverage Query Coverage Subject Accesion Number Product (Click to view blast result)
1567.0000 0.0 100.0000 100.0000 P17794 Protein virB4 precursor


Protein localization analysis
Psort (output)