ORF information
ORF ID TF00213 (frame 1) Gene ID BRA0062
Position and sequences 59906...60625(239 aa) Gene Name/synonym virB8 /virB8sp
Organism Brucella suis 1330 Cluster 47 genes
Product Type IV secretion system protein VirB8 homolog
1stcategory P-T4SS 2ndcategory VirB8 Family
3rdcategory Effector translocator
Function The VirB T4SS could be required for the establishment of the replication niche in the host. VirB8 forms a dimeric subunit, which is an essential core component of T4SS that undergoes multiple protein-protein interactions.
Miscellaneus VirB system is specifically induced within macrophages by phagosome acidification. Induced at 37 degrees Celsius in minimal medium, suggesting that nutritional stress is a regulating signal. PDB 2BHM;
References PubMed:11830669 

Functional Annotation
  KEGG database
Organism B.abortus Gene entry BruAb2_006
Gene name virB Synonyms 8
Definition type IV secretion system protein VirB8
Class Genetic Information Processing; Sorting and Degradation; Type IV secretion system [PATH:bmb03080]
Classification Sorting and Degradation
DBLinks GeneID 3342140 GI 62317021 UniProt Q7BMZ6
 
  COG Clusters of Orthologous Groups of proteins
 
Gene Classification Coords (size) Product
U 25 .. 239 (215) Type IV secretory pathway, component VirB8

Blast results (KEGG)
B.abortus :  BlastP (output)
Score Expect Query coverage Subject coverage
483 e-135 100 100

InterPro
Evidence ID Name Loci start-end InterPro ID InterPro Name
HMMPfam PF04335 VirB8 [ 0 - 232 ] IPR007430 VirB8
GO (Gene Onthology)
 
GO No results found !

Blast Results (Swiss-Prot)
Score Expect Coverage Query Coverage Subject Accesion Number Product (Click to view blast result)
483 e-136 100 100 Q7CEG3 Type IV secretion system protein virB8

Topology
 
PHOBIUS txt

Protein localization analysis
 
Psort bacterial inner membrane-0.272-Affirmative (output)