ORF information
ORF ID TF01703 (frame 1) Gene ID lpp0508
Position and sequences 550265...550609(114 aa) Gene Name/synonym icmS -
Organism Legionella pneumophila Paris Cluster 4 genes
Product Type IV secretion system protein IcmS
1stcategory I-T4SS 2ndcategory Uncharacterized Protein Family IcmS
3rdcategory Effector translocator
Function Component of the type IV secretion system Dot/Icm that is required for intracellular growth in human macrophages and amoebae. IcmS is not required for pore-formation, attachment of host vesicles to the L.pneumophila phagosome, and recruitment of the RER. Also, IcmS is not necessary for L.pneumophila replication in HL-60 derived human macrophages.
Miscellaneus IcmS is a cytoplasmic protein.
References PubMed:16803597  PubMed:18069892  PubMed:17040490  PubMed:15271914  PubMed:15003709  PubMed:14715899  PubMed:12081952  PubMed:10225863  PubMed:9488381  PubMed:9465074 

Functional Annotation
  KEGG database
Organism L.pneumophila_Corby Gene entry LPC_2901
Gene name icmS Synonyms
Definition IcmS
Classification Unassigned
DBLinks GeneID 5182679 GI 148360941
 
 
COG No results found !

Blast results (KEGG)
L.pneumophila_Corby :  BlastP (output)
Score Expect Query coverage Subject coverage
231 6e-60 100 100

InterPro
Evidence ID Name Loci start-end InterPro ID InterPro Name
ScanRegExp PS00238 OPSIN [ 0 - 21 ] IPR001760 Opsin

GO (Gene Onthology)
ID Type Description
0001584 Molecular Function rhodopsin-like receptor activity
0007186 Biological Process G-protein coupled receptor protein signaling pathway
0007601 Biological Process visual perception
0016021 Cellular Component integral to membrane
Blast Results (Swiss-Prot)
 
Blast Results (Swiss-Prot) No results found !

Topology
 
PHOBIUS txt

Protein localization analysis
 
Psort bacterial cytoplasm-0.2877-Affirmative (output)