ORF ID | TF01702 (frame 1) |
Gene ID | lpl0484 |
Position and sequences | 526307...526651(114 aa) |
Gene Name/synonym |
icmS
- |
Organism | Legionella pneumophila Lens |
Cluster |
4 genes |
Product | Type IV secretion system protein IcmS |
1stcategory | I-T4SS |
2ndcategory | Uncharacterized Protein Family IcmS |
3rdcategory | Effector translocator |
Function | Component of the type IV secretion system Dot/Icm that is required for intracellular growth in human macrophages and amoebae. IcmS is not required for pore-formation, attachment of host vesicles to the L.pneumophila phagosome, and recruitment of the RER. Also, IcmS is not necessary for L.pneumophila replication in HL-60 derived human macrophages. |
Miscellaneus | IcmS is a cytoplasmic protein.
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References |
PubMed:16803597 
PubMed:18069892 
PubMed:17040490 
PubMed:15271914 
PubMed:15003709 
PubMed:14715899 
PubMed:12081952 
PubMed:10225863 
PubMed:9488381 
PubMed:9465074 
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