ORF information
ORF ID TF01685 (frame 1) Gene ID lpl0492
Position and sequences 533370...534452(360 aa) Gene Name/synonym icmK /dotH
Organism Legionella pneumophila Lens Cluster 6 genes
Product Type IV secretion system protein IcmK/DotH
1stcategory I-T4SS 2ndcategory Uncharacterized Protein Family IcmK/DotH
3rdcategory Effector translocator
Function Component of the type IV secretion system Dot/Icm that is required for intracellular growth in human macrophages and amoebae. IcmK/DotH is associated with a fibrous structure that covers the entire bacterial surface, which may act either just before lysis from the macrophage or at earlier stages of infection.
Miscellaneus
References PubMed:11136453  PubMed:17040490  PubMed:15271914  PubMed:15003709  PubMed:14715899  PubMed:12081952  PubMed:10225863  PubMed:9488381  PubMed:9465074 

Functional Annotation
  KEGG database
Organism L.pneumophila_Lens Gene entry lpl0492
Gene name icmK Synonyms dotH
Definition hypothetical protein
Classification Unassigned
DBLinks GeneID 3116071 GI 54293443 Pasteur lpl0492 UniProt Q5WZ90
 
 
COG No results found !

Blast results (KEGG)
L.pneumophila_Lens :  BlastP (output)
Score Expect Query coverage Subject coverage
724 0.0 100 100

InterPro
Evidence ID Name Loci start-end InterPro ID InterPro Name
ProfileScan PS51257 PROKAR_LIPOPROTEIN [ 0 - 22 ] NULL NULL
GO (Gene Onthology)
 
GO No results found !
Blast Results (Swiss-Prot)
 
Blast Results (Swiss-Prot) No results found !

Topology
 
PHOBIUS txt

Protein localization analysis
 
Psort bacterial inner membrane-0.1786-Affirmative (output)