ORF ID | TF01685 (frame 1) |
Gene ID | lpl0492 |
Position and sequences | 533370...534452(360 aa) |
Gene Name/synonym |
icmK
/dotH |
Organism | Legionella pneumophila Lens |
Cluster |
6 genes |
Product | Type IV secretion system protein IcmK/DotH |
1stcategory | I-T4SS |
2ndcategory | Uncharacterized Protein Family IcmK/DotH |
3rdcategory | Effector translocator |
Function | Component of the type IV secretion system Dot/Icm that is required for intracellular growth in human macrophages and amoebae. IcmK/DotH is associated with a fibrous structure that covers the entire bacterial surface, which may act either just before lysis from the macrophage or at earlier stages of infection. |
Miscellaneus |
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References |
PubMed:11136453 
PubMed:17040490 
PubMed:15271914 
PubMed:15003709 
PubMed:14715899 
PubMed:12081952 
PubMed:10225863 
PubMed:9488381 
PubMed:9465074 
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