| ORF ID | TF01677 (frame 1) |
Gene ID | lpg0456 |
| Position and sequences | 493271...496300(1009 aa) |
Gene Name/synonym |
icmB
/dotO |
| Organism | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 |
Cluster |
7 genes |
| Product | Type IV secretion system protein IcmB/DotO |
| 1stcategory | I-T4SS |
2ndcategory | Uncharacterized Protein Family IcmB/DotO |
| 3rdcategory | Effector translocator |
| Function | Component of the type IV secretion system Dot/Icm that is required for intracellular growth in human macrophages and amoebae. IcmB/DotO is associated with a fibrous structure that covers the entire bacterial surface, which may act either just before lysis from the macrophage or at earlier stages of infection. |
| Miscellaneus |
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| References |
PubMed:11136453
PubMed:17040490
PubMed:15271914
PubMed:15003709
PubMed:14715899
PubMed:12081952
PubMed:10225863
PubMed:9488381
PubMed:9465074
PubMed:10564519
|