ORF information
ORF ID TF01663 (frame 1) Gene ID lpp0524
Position and sequences 568647...571568(973 aa) Gene Name/synonym icmF -
Organism Legionella pneumophila Paris Cluster 32 genes
Product Type IV secretion system protein IcmF
1stcategory I-T4SS 2ndcategory IcmF-related Family
3rdcategory Effector translocator
Function Component of the type IV secretion system Dot/Icm that is required for intracellular growth in human macrophages and amoebae. Altogether with IcmH/DotU, icmF is required for intracellular multiplication in Acanthamoeba castellani and partially required for intracellular growth in HL-60 derived human macrophages, as well as for pore formation.
Miscellaneus
References PubMed:15155646  PubMed:17040490  PubMed:15271914  PubMed:15003709  PubMed:14715899  PubMed:12081952  PubMed:10225863  PubMed:9488381  PubMed:9465074 

Functional Annotation
  KEGG database
Organism L.pneumophila_Paris Gene entry lpp0524
Gene name icmF Synonyms
Definition hypothetical protein
Classification Unassigned
DBLinks GeneID 3117270 GI 54296493 Pasteur lpp0524 UniProt Q5X7T1
 
 
COG No results found !

Blast results (KEGG)
L.pneumophila_Paris :  BlastP (output)
Score Expect Query coverage Subject coverage
1925 0.0 100 100

InterPro
Evidence ID Name Loci start-end InterPro ID InterPro Name
HMMTigr TIGR03348 VI_IcmF [ 0 - 970 ] IPR017731 Type VI secretion system, IcmF
GO (Gene Onthology)
 
GO No results found !
Blast Results (Swiss-Prot)
 
Blast Results (Swiss-Prot) No results found !

Topology
 
PHOBIUS txt

Protein localization analysis
 
Psort (output)