ORF ID | TF01662 (frame 1) |
Gene ID | lpl0500 |
Position and sequences | 544714...547635(973 aa) |
Gene Name/synonym |
icmF
- |
Organism | Legionella pneumophila Lens |
Cluster |
32 genes |
Product | Type IV secretion system protein IcmF |
1stcategory | I-T4SS |
2ndcategory | IcmF-related Family |
3rdcategory | Effector translocator |
Function | Component of the type IV secretion system Dot/Icm that is required for intracellular growth in human macrophages and amoebae. Altogether with IcmH/DotU, icmF is required for intracellular multiplication in Acanthamoeba castellani and partially required for intracellular growth in HL-60 derived human macrophages, as well as for pore formation. |
Miscellaneus |
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References |
PubMed:15155646 
PubMed:17040490 
PubMed:15271914 
PubMed:15003709 
PubMed:14715899 
PubMed:12081952 
PubMed:10225863 
PubMed:9488381 
PubMed:9465074 
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