ORF ID | TF01006 (frame 1) |
Gene ID | pIncPalpha_00315 |
Position and sequences | 46588...48495(635 aa) |
Gene Name/synonym |
traG
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Organism | Birmingham IncP-alpha plasmid |
Cluster |
67 genes |
Product | Conjugal transfer protein TraG |
1stcategory | P-T4SS |
2ndcategory | VirD4/TraG Family |
3rdcategory | Conjugation |
Function | Component of the Tra system that constitutes the Tra1 block, which is mainly concerned with triggering DNA transfer. TraG is essential for mobilization of IncP plasmids. May bind tightly and specifically to the relaxase traI. May also bind to DNA without sequence specificity. May form a pore-like structure that could serve as a channel for DNA transfer. |
Miscellaneus | For transfer the plasmid requires two blocks of genes. The transfer origin, oriT and genes traA to traM constitute the Tra1 block, which is mainly concerned with triggering DNA transfer, while the genes trbA to trbP form a Tra2 operon concerned mainly with mating pair formation.
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References |
PubMed:8954881 
PubMed:11976307 
PubMed:8021214 
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